Dopamine (3-hydroxytyramine) metabolism in parkinsonism.

Dopamine (3-Hydroxytyramine) Replacement and Metabolism

METHODS General Three severely burned patients were infused with dopamine-2-uC (3-hydroxytyramine, 3,4-dihydroxyphenylethylamine), the immediate precursor in the biosynthesis of noradrenaline (see Fig. 1). Infusion was purposely delayed until 3 wk after the burn, since it is at this time that the depletion of adrenaline and noradrenaline most commonly manifests itself (6, 10, 11). Whereas, the ...

Synthesis of novel dopamine derived multidirectional ligands from cyanuric chloride: structural and antimicrobial studies

Two monopodal (2,4-dichloro-6-(3-hydroxytyramine)-1,3,5-triazine) and tripodal (2,4,6-(3-hydroxytyramine)-1,3,5-triazine) s-triazine derivatives were prepared through the reaction of cyanuric chloride (2,4,6-trichloro-1,3,5-triazine) and 3-hydroxytyramine hydrochloride (dopamine hydrochloride). The structures of the compounds were identified by FT-IR, 1H NMR, 13C NMR, thermal analysis and eleme...

Development and Validation of a Spectrophotometric Enzymatic Assay Method for the Quantification of Uric Acid by Using 3 - Hydroxytyramine as a Chromogenic Substrate

Separation of adrenaline, noradrenaline, and hydroxytyramine by ion exchange chromatography.

Methods for the separation of adrenaline, noradrenaline, hydroxytyramine, and dihydroxyphenylalanine (dopa) by employing starch columns (2, 3), paper chromatography (4-7), or countercurrent extraction (8) have limited usage either because of the length of time required for the fractionation or because of the small amounts of material that can be separated. A procedure is described below in whic...

Ethylene formation in sugar beet leaves: evidence for the involvement of 3-hydroxytyramine and phenoloxidase after wounding.

Ethylene production by sugar beet (Beta vulgaris L.) leaf discs is inhibited by white (or red, >610 nm) light or by wounding. In contrast, in wounded leaf discs, ethylene production is stimulated by light. The effect of light on wounded leaf discs has been studied by using an in vitro system which mimics the loss of compartmentation in the wounded leaf. Chlorophyll-free extracts from sugar beet...